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Ten63 Therapeutics and Boehringer Ingelheim Enter Partnership for Multi-Target Drug Discovery

Thursday, December 07, 2023

Ten63 Therapeutics, a biotechnology company, has unveiled a collaboration with Boehringer Ingelheim for multi-target drug discovery. The partnership aims to discover innovative therapeutic molecules to address diseases that conventional drug discovery methods have been unable to target effectively, meeting the high unmet needs of patients.

The collaboration will leverage Ten63's computational drug discovery engine, BEYOND, to identify novel molecules for various targets specified by Boehringer Ingelheim across diverse indications. Boehringer Ingelheim will contribute its expertise in pre-clinical discovery and drug development to enhance the overall drug discovery process.

Dr. Marcel Frenkel, CEO of Ten63, expressed pride in the collaboration, stating that Ten63 is excited to work with Boehringer Ingelheim to discover molecules that could significantly impact human lives. The synergy between Ten63's BEYOND platform and Boehringer Ingelheim's leading capabilities in discovery and development is anticipated to yield groundbreaking therapeutics for patients.

The BEYOND platform comprises a suite of proprietary algorithms designed to facilitate drug discovery for targets that are traditionally challenging for conventional technologies. BEYOND integrates cryptic pocket discovery with a data-independent and interpretable generative chemistry engine to identify potent drug candidates. By exploring the conformational and chemical space of over 100 trillion synthetically feasible drug-like molecules, BEYOND aims to discover optimal solutions using advanced models. Additionally, BEYOND continually learns from each iteration of chemistry, incorporating target-specific data and models based on extensive external datasets to accurately predict multiple absorption, distribution, metabolism, and excretion (ADME) properties in new chemical space.



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