The Research Insights area highlights recent advances in science and medicine as well as global laboratory research. Our readers gain tremendous benefit from research discoveries in an indirect manner.
Prion diseases are fatal neurodegenerative diseases that uniquely occur in inherited sporadic and infectious forms All forms of prion diseases are caused by autocatalytic misfolding of the prion protein
Many natural peptides have been identified as important regulators of biological functions acting as hormones ion channels and GPCR modulators growth factors and neurotransmitters
Allelic variation in genes that regulate immune cell responses potentially impact an individuals response to self and foreign antigens Genome wide association studies have identified variants in immunerelated genes
Rapid advances in CRISPRCas and other genome editing technologies are transforming our ability to engineer the properties of cells The ability to deploy these technologies at scale offers unprecedented opportunities for both research and clinical applications
Antiseizure medications are the mainstay of therapy in the management of epilepsy and are indicated for patients who have experienced two or more unprovoked seizures or a single unprovoked seizure accompanied by additional
Osteoporosis is a systemic skeletal condition marked by reduced bone density compromised bone quality and strength resulting in heightened bone fragility and a greater likelihood of fractures
Osteoarthritis is a complex joint disorder with multifactorial etiology characterized by the manifestation of joint pain restricted joint mobility and the potential for functional impairment The pathogenesis of OA is characterized by synovitis
As a common pathological type of nonsmall cell lung cancer lung adenocarcinoma is mostly located in the bronchial mucosal epithelium Typical symptoms of the disease are hemoptysis cough and shortness of breath
Lung cancer is one of the major causes of cancer death worldwide and the most frequent cancer in men Although in the last decades there has been considerable research to understand its biological and clinical aspects the overall survival remains poor
The recent COVID pandemic caused by the severe acute respiratory syndrome coronavirus further intensified the study of hostpathogen interactions and the mechanisms through which viruses suppress cellular antiviral responses
