The Research Insights area highlights recent advances in science and medicine as well as global laboratory research. Our readers gain tremendous benefit from research discoveries in an indirect manner.
Menthol exerts relaxing antibacterial and antiinflammatory activities and is marketed as a functional food and therapeutic drug
Chromatin the assembly of DNA RNA and proteins that constitutes chromosomes can assume active and inactive states that are correlated with different histone and DNA modifications Transcriptionally inactive
Congenital metabolic disorders CMDs arise from genetic mutations that result in reduction or absence of enzymatic activity leading to phenotypic clinical manifestations Although most CMDs are rare individually
During C elegans oocyte meiosis I cytokinesis and polar body extrusion cortical actomyosin is locally remodeled to assemble a contractile ring that forms within and remains part of a much larger and actively contractile cortical actomyosin network
The ability to alter gene expression programs in response to changes in environmental conditions is central to the ability of an organism to thrive For most organisms the nervous system serves as the master regulator in communicating information
Translational control is critical for cell fate transitions during development lineage specification and tumorigenesis Here we show that the transcription factor double homeobox protein DUX and its previously characterized transcriptional program
Pentavalent vaccines DTPHepBHib have been introduced in many countries in their routine public immunization programmes to protect against diphtheria D tetanus T pertussis P hepatitis B Hep B and Hemophilus influenzae type b Hib diseases
The mitochondrial CtoU RNA editing factor PPR of the moss Physcomitrium patens is an RNAbinding pentatricopeptide repeat protein equipped with a terminal DYWtype cytidine deaminase domain
A highly ordered functional neuronal circuit comprises polarized nerve cells which are compartmentalized into dendrites and axons for unidirectional reception and transmission of information
As soon as they emerge from the ribosomal tunnel the protein nascent chains recruit factors that will play key roles in their life cycle Such recruitment is dependent on the nature of the protein Nterminal amino acid residues
