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App Note: QuantStudio 7 pro qPCR systems

See how QuantStudio systems and consumables generate consistent results across instruments and operators to help ensure data concordance.

See how QuantStudio systems and consumables generate consistent results across instruments and operators to help ensure data concordance.

 

Use-cases in the mRNA and protein-based vaccines pipeline

Discovery

  • Antigen identification
  • Lead antigen selection
  • Antibody screening
  • Biomarker identification
  • Biomarker screening

Process development

  • Plasmid construction and mRNA packaging (mRNA vaccines)
  • Vector construction, cell growth, and protein purification (protein vaccines)
  • Quality Control test development
  • Scale-up
  • In-process test development
  • Impurity and contamination testing
  • Residual host-cell DNA

Pre-clinical and clinical trials

  • Pharmacokinetics & pharmacodynamics studies
  • Potency testing
  • Biodistribution analysis

cGMP manufacturing

  • In-process testing and lot release
  • Impurity and contamination testing
  • Viral clearance
  • Bioburden
  • Residual host-cell DNA

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