What are the challenges in antibody drug discovery — and how can they be addressed
Antibody discovery requires optimization across multiple dimensions, including target engagement, functional activity, immunogenicity, and developability.
Antibody discovery requires optimization across multiple dimensions, including target engagement, functional activity, immunogenicity, and developability. Connected, data-driven workflows help teams make better decisions earlier and continuously improve antibody candidates.
key points:
- Integrate sequence design and molecular modeling across antibody variants.
- Combine functional testing with developability assessment.
- Connect design and experimental data to prioritize stronger candidates.