How can researchers navigate the complexity of RNA drug discovery

RNA therapeutics are becoming increasingly complex through chemical modifications, delivery strategies, and diverse RNA modalities such as mRNA, siRNA, ASOs, and circRNA.

Standardized molecular representation and connected digital workflows help researchers manage complexity and accelerate RNA drug development.

key points:

• Use HELM to design and visualize complex RNA architectures.
• Connect RNA design, synthesis, and testing in one workflow.
• Integrate data analysis to support candidate selection.