Research Insights
The Research Insights area highlights recent advances in science and medicine as well as global laboratory research. Our readers gain tremendous benefit from research discoveries in an indirect manner.
Impact of COVID-19 on Patterns of Drug Utilization: A Case Study at National Hospital
The Coronavirus disease of COVID pandemic and the corresponding mitigation measures have had a discernible impact on drug utilization among outpatients
Exploring the Resistance Mechanism of Triple-negative Breast Cancer to Paclitaxel Through the scRNA-seq Analysis
The triple negative breast cancer is the most malignant subtype of breast cancer with high aggressiveness Although paclitaxelbased chemotherapy scenario present the mainstay in TNBC treatment
NeuroD1-GPX4 signaling leads to ferroptosis resistance in hepatocellular carcinoma
Cell death resistance is one of the hallmarks of cancer The balance of cell death plays a vital role in regulating cell population size and tumorigenesis Cell death can be classified as accidental cell death threshold has attracted attention as a potential antitumor therapeutic strategy
Characterization of a Novel Bacteriophage Endolysin (LysAB1245) With Extended Lytic Activity Against Distinct Capsular Types Associated With Acinetobacter Baumannii Resistance
Recently an outbreak of A baumannii infections in coronavirus disease patients has been reported resulting in increased morbidity and mortality rates as well as high treatment costs
Feasibility and Metabolic Outcomes of a Well-formulated Ketogenic Diet as an Adjuvant Therapeutic Intervention for Women With Stage IV Metastatic Breast Cancer
In breast cancer became the most diagnosed cancer worldwidewith an estimated million new casessurpassing lung cancer Early detection and treatment have improved breast cancer survival rates to almost
Many but Not All Deep Neural Network Audio Models Capture Brain Responses and Exhibit Correspondence Between Model Stages and Brain Regions
An overarching aim of neuroscience is to build quantitatively accurate computational models of sensory systems Success entails models that take sensory signals as input and reproduce the behavioral judgments mediated by a sensory system as well as its internal representations
A New Variant of the Colistin Resistance Gene MCR-1 With Co-resistance to Β-lactam Antibiotics Reveals a Potential Novel Antimicrobial Peptide
ColistinPolymyxin is a lastresort antibiotic against infections caused by highly drugresistant bacteria particularly carbapenemresistant Enterobacterales However the emergence of a novel plasmidmediated colistin resistance gene named mcr in threatened the clinical effectiveness of colistin
Potential Drug–drug Interactions of Frequently Prescribed Medications in Long COVID Detected by Two Electronic Databases
The focus of this study was on frequently prescribed medications for patients with both long COVID and other common chronic conditions such as diabetes mellitus hypertension dyslipidemia and chronic infections
Vaccinomics-aided Next-generation Novel Multi-epitope-based Vaccine Engineering Against Multidrug Resistant Shigella Sonnei: Immunoinformatics and Chemoinformatics Approaches
Shigella sonnei is a gramnegative bacterium and is the primary cause of shigellosis in advanced countries An exceptional rise in the prevalence of the disease has been reported in Asia the Middle East and Latin America
Antimicrobial Drug Resistant Features of Mycobacterium Tuberculosis Associated With Treatment Failure
Tuberculosis stands as a prominent cause of mortality in developing countries The treatment of tuberculosis involves a complex procedure requiring the administration of a panel of at least four antimicrobial drugs for the duration of six months
