Pharma Articles
Renowned pharmaceutical firm executives and other experts from around the world write articles on current topics in the industry. The section of articles on the pharmaceutical sector focuses on contemporary and expanding challenges in fields such as pharmaceutical R&D, drug discovery, clinical trials, pharmaceutical production, biopharmaceuticals, and information technology.
Using AI to Improve Drug Repurposing and Molecule Discovery
Every pharmaceutical company owns more knowledge than it can use Approved medicines carry years of safety dosing and manufacturing data Shelved compounds sit in archives with toxicology packages already complete Decades of assay results clinical observations and published literature describe how mol...
How Biosimilars Are Changing Competition in the U.S. Drug Market
For most of the past decade biosimilars were treated in American boardrooms as a slowburning nuisance a regulatory pathway that existed on paper produced a trickle of approvals and rarely threatened a flagship biologic in a meaningful way That view is now dangerously out of date
How Pharma Companies Are Building Commercial Strategies for High-Cost Therapies
American medicine has entered an era in which a single treatment can deliver decades of benefit and in some cases a potential cure after one administration Gene therapies for inherited blood disorders engineered cell therapies for cancer and advanced treatments for rare neuromuscular and metabolic d...
Pharmaceutical Compliance and Ethical Practices in the U.S. Market
Ask anyone whos worked inside a pharmaceutical company for more than a few years and theyll tell you compliance used to feel like paperwork something the legal department handled while everyone else focused on real work That mindset has mostly disappeared and for good reason
Adaptive Trial Designs: Enhancing Speed and Decision-Making in Clinical Development
A conventional clinical trial is a sealed envelope The sponsor fixes the sample size the doses the patient population and the analysis plan then enrolls for years without looking inside Only at the end does the organization learn whether its assumptions were right If the assumed effect size was too...
Building Resilient Pharma Supply Chains Through Digital Twins and AI
Ask a US pharmaceutical executive when they learned about their last serious supply disruption and the answer is rarely encouraging Not when the upstream suppliers yield began drifting Not when a secondtier vendor quietly extended lead times Usually the news arrived when a purchase order could not b...
Future-Proofing Biopharma: Integrating AI, Advanced Modalities, and Smart Manufacturing
For decades the US biopharmaceutical industry organized itself in sequence Scientists discovered a molecule developers proved it worked and manufacturing teams worked out how to make it at scale often late and under pressure That relay model was tolerable when most medicines were small molecules pro...
Next-Generation Immunotherapies: Innovations Beyond CAR-T
Few therapeutic classes have changed oncology as quickly as CART Within a decade a laboratory concept became a commercial reality capable of producing complete yearslong remissions in patients
The Evolution of Sterile API Manufacturing for Advanced Injectable Therapies
The Bottleneck Nobody Toured Sterile API Manufacturing Moves to the Boardroom Almost every conversation about US injectable capacity is a conversation about fillfinish Lines isolators vials prefilled syringes robotic filling that is where the investment announcements and the plant tours happen
How AI Is Changing Drug Discovery and Pharmaceutical R&D in the U.S.
For most of the past decade the AI story in American drug discovery was told in forwardlooking statements In it can be told in outcomes An analysis presented at a major oncology congress this year counted AIenabled therapeutic assets across companies that had entered interventional human trials O...
